Local Disappearance of Epiphyseal Growth Plates in Rats with Hypervitaminosis A.
نویسندگان
چکیده
منابع مشابه
Local disappearance of epiphyseal growth plates in rats with hypervitaminosis A.
Epiphyseal growth plates of proximal tibiae in rats with high doses of vitamin A (V-A) were observed. Of 4 groups, each consisting of 5 rats, three groups were given V-A at doses, IU/100 g by body weight/day, of 50,000, 100,000, and 150,000, respectively. The other group rats were given no V-A (control). Rats were administered V-A for the 5 days from 4 weeks after birth and sacrificed at 12 wee...
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This study was carried out to prove the possibility of inhibition of long bones epiphyseal plates activity with photodynamic impact. Comparative analysis of the Chlorin E6 accumulation with transcutaneous and intraperitoneal administration mode, carried out on 175 laboratory mice showed the drug accumulates selectively in the epiphyseal plates of long bones, regardless of the mode of administra...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 1998
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.60.815